June 12-14, 2003, Olsztyn - Poland
12.06.2003
9:00
Registration
12:30-14:30
Lunch
14:45
WELCOME AND OPENING OF THE WORKSHOP
Mariusz Piskuła - Chairman of Workshop Organising Committee
Halina Kozłowska - Co-ordinator of CENEXFOOD
Roger Fenwick - Chairman of CENEXFOOD Scientific Board
SESSION 1
MODELS
USED IN RESEARCH ON BIOLOGICAL ACTIVITY OF POLYPHENOLS, EXAMPLES
AND CRITICAL EVALUATION
Chairpersons: Peter Hollman, Maria Kapiszewska
15:00
Paul Kroon, IFR, Norwich, United Kingdom
"Absorption
and metabolism of polyphenols: What can we learn from in vitro models
and how does it compare with human studies?"
15:30
Gary Williamson, Nestle Research Centre, Lausanne,
Switzerland
"Effects of polyphenol metabolism on gene
expression in vivo"
16:00
Coffee Break
16:15
Antoni Nasal, Medical School, Gdańsk, Poland
"Application
of chemometrics to HPLC data processing aimed at the prediction
of bioactivity of xenobiotics"
16:45
Junji Terao, University of Tokushima, Tokushima, Japan
"Antioxidant
activity of flavonoids in different animal model systems
- in vitro, ex vivo and in vivo"
20:00
WORKSHOP DINNER
Restaurant "Przystań" (transportation from Park Hotel provided)
13.06.2003
SESSION 2
ETHICAL ASPECTS
IN BIOLOGICAL RESEARCH
Chairpersons: Roger Fenwick, Mariusz Piskuła
9:30
David Coles, Unit Ethics in Science and Research,
Brussels, European Commission
"Ethical review on research
projects under FP6"
10:00
Liz Lund, IFR, Norwich, United Kingdom
"Ethical
aspects of human nutritional intervention studies – a British
view point"
10:30
Zenon Zduńczyk, Institute of Animal Reproduction and Food
Research Olsztyn, Poland,
"Ethical and legal conditions
for using animals in research"
11:00
Coffee Break
11:15 - 12:15
Workshop Poster Session
12:30
Lunch
SESSION 3
BIOLOGICAL ACTIVITY OF PHYTOCHEMICALS, FROM SCIENTIFIC INTEREST
TO STUDY TO POTENTIAL HEALTH EFFECT
Chairpersons: Junji Terao, Gary Williamson
13:30
Peter Hollman, TNO, Wageningen, Netherlands
"Evidence
for health benefits of flavonoids"
14:00
Zenon Czuba, Silesian School of Medicine, Zabrze, Poland
"Influence of polyphenols on macrophage cells"
14:30
Coffee break
14:45
Maria Kapiszewska, Jagiellonian University, Kraków,
Poland,
"The COMT-mediated metabolism of flavonoids
and estrogen and its relevance to the cancer risk"
15:15
Tojiro Tsushida, National Food Research Institute, Tsukuba,
Japan
"Evaluation of physiological functionalities of
some flavonoids using animal cell culture."
15:45
Marek Snochowski, The Kielanowski Institute of Animal Physiology and
Nutrition, Jablonna, Poland
"The use of estrogen receptors for
evaluation of phytoestrogens activities in mammals."
16:15
Coffee break
16:30
Round table discussion
17:30
Closing remarks
19:00
Dinner at Hotel Park
(members of CENEXFOOD SCIENTIFIC BOARD
will accompany)
14.06.2003
Departure, for participants leaving on Sunday - social event
optional
(sightseeing, golf, fishing)
LIST OF POSTER PRESENTATIONS
The effect of plant phenolics on the processes involved in the initiation and promotion of carcinnogenesis in mouse skin
W. Baer-Dubowska, H. Szaefer, M. Cichocki, M. Zielińska
Department of Pharmaceutical Biochemistry, University of Medical Sciences, Poznań, Poland
ORAC-fluorescein as a model for evaluating antioxidant activity of wines
A. Dávalos, B. Bartolomé, C. Gómez-Cordovés
Instituto de Fermentaciones Industriales, CSIC, Madrid, Spain
Cytotoxic and genotixic effects of cabbage and beetroot juice towards HT29 colon tumour cell line
J. Grześkowiak, A. Bujnowska, A.Bartoszek
Department of Pharmaceutical Technology and Biochemistry, Gdańsk University of Technology, Poland
Antioxidant capacity of crude phenolic extracts from wild blueberry leaves
M. Naczk1, R. Amarowicz2, R. Zadernowski3, R. Pegg4, F. Shahidi4
1Department of Human Nutrition, St. Francis Xavier University, Antigonish, NS, Canada;
2Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland;
3Faculty of Food Science, Warmia and Mazury University, Olsztyn Poland;
4Department of Biochemistry, Memorial University of Newfoundland, St John's, NF, Canada
Antioxidant activity and total phenolics in fruits
A. Podsędek, D. Sosnowska
Institute of Technical Biochemistry, Technical University of Łódź, Poland
Antioxidative properties of berry fruits and beverages with their addition
A. Szajdek
Chair of Food Plant Chemistry and Processing, Univeristy of Warmia and Mazury, Olsztyn, Poland
A new HPLC method for the direct determination of chlorogenic acid in cichorum
B. Król, I. Gałązka, K. Grzelak
Institute of Chemical Technology of Food, Technical University of Łódź, Poland
Exploring reflectance spectra of apple slices and their relation to active phenolic compounds
A. Kuczyński
Institute of Agrophysics, Polish Academy of Sciences, Lublin, Poland
Influence of grapefruit flavonoids on mineral absorption in rats
S. Frejnagel1, E. Gomez-Villalva2, G. Urbano2, Z Zduńczyk1
1Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland;
2Departamento de Fisiologia, Facultad de Farmacia, Universidad de Granada, Spain
Evaluation of processing influence on onion flavonoids
K. Németh1, M. Piskuła2
1Slovak Technical University, Bratislava, Slovak Republic;
2Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
Bioavailability of quercetin from fresh scales and dry skin of onion in rats
W.Wiczkowski1, K. Németh2, A.Buciński1, M.Piskuła1
1Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland;
2Slovak Technical University, Bratislava, Slovak Republic
Sensory and chemical aspects of astringency of phenolic compounds from grain legume seeds
A. Troszyńska1, H.Kmita-Głażewska1,G.Lamparski1, N. Baryłko-Pikielna2
1Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland;
2Department of Food Technology, Warsaw Agricultural University, Warsaw, Poland
Principal Component Analysis (PCA) as an objective tool for determination of similarity between (Allium cepa L.) and shallot (Allium cepa L. var. aggregatum G.Don.) cultivars based on quercetin and its derivatives
A. Buciński1, W. Wiczkowski1, T. Kotlińska2, M. Piskuła1
1Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland;
2Genetic Resources Laboratory of Research Institute of Vegetable Crops, Skierniewice, Poland