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Name of Department: Department of Reproductive Immunology and Pathology
Work title: „The participation of ovarian steroids and interleukins in pathogenesis of equine endometrial fibrosis” (working title).
Doctor thesis advisor: prof. dr. hab. D.J. Skarżyński
Professional preparation:
Education
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2003 – 2008 Faculty of Biology, Specialization of Biotechnology, University of Warmia and Mazury, Olsztyn. Science Master degree in Biotechnology. A master work title: „ Does tumor necrosis factor-α modulates sensitivity of bovine corpus luteum to selected luteotropic factors?”. Master’s thesis advisor was prof. dr. hab. D.J. Skarżyński from Department of Reproductive Immunology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland.
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01.10.2008 – present – candidate for doctor’s degree in Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences.
Practice
Course and workshop
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23.10 - 25.10.2008 Workshop „Closer to word-control of mammals, birds and fishes males reproduction ”. Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland.
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05.03 - 07.03.2009 Workshop „Genomics and proteomics” organized by „MBS” Service for Molecular Biology, Warsaw, Poland.
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04.05 -15.05.2009 „ VIII Course on Laboratory Animals Science” Faculty of Veterinary Medicine, Technical University of Lisbon in Portugal.
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08.10 - 10.10.2009 – Course „Animal cells: culture, transfection and gene suppressing” organized by „MBS” Service for Molecular Biology, Warsaw, Poland.
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01.07 - 03.07.2010 – Course „Real-time PCR” organized by „MBS” Service for Molecular Biology, Warsaw, Poland.
Communications:
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Szóstek AZ, Lukasik K, Bah MM, Skrzynski DJ. ,,Czy czynnik martwicy nowotworu alfa moduluje wrazliwosc cialka zóltego krowy na czynniki luteotropowe?" Wroclaw 10 - 13. 09. 2008. V Jubilee Symposium of Society for Biology of Reproduction. (poster)
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Majewska M, Hwa-Yong Lee, Szóstek AZ, Okuda K, Skarzynski D.J. „Effects of interferonon cortisol production by the bovine endometrial tissues.” Biology of Reproduction 81:602. (poster)
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Valente L, Galvão A, Szóstek AZ, Skarzynski DJ, Ferreira-Dias G. “Equine endometrial eells: cytokine and hormones action on angiogenic activity. Reproduction in Domestic Animals 44 (Suppl 3): 92 (Abst P91). (poster)
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Galvão A, Ramilo D, Mateus L, Szóstek AZ, Skarzynski DJ, Ferreira-Dias G. “Expression of cytokines and their receptors in the equine endometrium during the estrous cycle” Reproduction in Domestic Animals 44 (Suppl 3): 84 (Abst P31). (poster)
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Szóstek AZ, Galvão A, Skarzynski DJ, Ferreira-Dias G. „Preliminary studiem on isolation, culture and cryoconservation of the epithelial and stromal cells from the equine uterus-technical report”. Meeting of the COST Action GEMINI; 1-3 October 2009, Alghero, Italy. (poster)
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Majewska M, Szóstek AZ, Siemieniuch MJ, Skarzynski DJ. (2010) Influence of cortisol on prostaglandin production in bovine endometrium in vitro. 3rd Annual COST GEMINI Meeting, 1 - 3 October 2010, Soustons, Francja. (poster)
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Skarzynski DJ, Szóstek AZ „Wpływ steroidów jajnikowych oraz wybranych cytokin prozapalnych na produkcję i wydzielanie prostaglandyn w macicy klaczy: model in vitro” I Meeting COST GEMINI 05.11.2010 Jastrzębiec. (oral speech)
Publications:
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Szóstek AZ, Lukasik K, Majewska M, Bah MM, Znaniecki R, Okuda K, Skarzynski DJ (2011) Tumor necrosis factor-α inhibits the stimulatory effect of luteinizing hormone- and prostaglandin E2 on progesterone secretion by the bovine corpus luteum. Domestic Animal Endocrinology x: 000-000.
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Ferreira-Dias G, Costa A.S, Mateus L, Korzekwa A.J, Galvao A.M., Redmer D.A, Lukasik K, Szóstek AZ, Woclawek-Potocka I, Skarzynski D.J (2011) Nitric Oxide stimulates progesterone and prostaglandin E2 secretion, and angiogenic activity in the equine corpus luteum during the early luteal phases. Domestic Animal Endocrinology Endocrinology 2011 (40): 1-9.
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Szóstek AZ, Siemieniuch MJ, Deptula K, Woclawek-Potocka I, Majewska M, Okuda K, Skarzynski DJ (2011) Ovarian steroids modulate tumor necrosis factor-α and nitric oxide regulated prostaglandins secretion by cultured bovine oviductal epithelial cells. Domestic Animal Endocrinology x: 000-000.
Another achievements:
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2008-2010 - a scholarship for Ph. D. students “DrINNO – zwiększenie podaży technologicznej w województwie warmińsko-mazurskim poprzez stypendia dla doktoranów” which main aim is an increase of technological supply on Warmia and Mazury. This scholarship have been awarded by Urząd Marszałkowski Województwa Warmińsko-Mazurskiego and supported by the European Union within the European Social Fund.
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Subcontractor in science project MNiSW nr 2P06K 025 29: „Czy stosowanie cytokin może stać się jedną z metod regulacji cyklu rujowego i terapii stanów zapalnych macicy w okresie okołoporodowym?” IRZBZ PAN in Olsztyn, 2005 - 2008.
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Subcontractor in science project Wykonawca w projekcie badawczym MNiSW nr N308 327 933: „Udział glikokortykosteroidów w mechanizmie działania sygnału płodowego - interferonu-τ: modulujący wpływ na syntezę i wydzielanie prostaglandyn w macicy krowy”; IRZBZ PAN in Olsztyn, 2007-2010.
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Subcontractor in science project MNiSW akcji COST FA0702 nr DPN N5/COST/2010: "Wpływ steroidów jajnikowych oraz wybranych cytokin prozapalnych na produkcję i wydzielanie prostaglandyn w macicy klaczy: model badawczy in vitro”.
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Subcontractor in science project MNiSW N308 560740: "Rola Czynnika Martwicy Nowotworu alfa (TNFalpha) w patogenezie zespołu endometritis-pyometra indukowanego lipopolisacharydem (LPS) u kotek w warunkach" IRZBŻ PAN, 2011-2014.
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Graduate studies