PAN Olsztyn

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Publikacje

Najnowsze publikacje

  1. Mlynarczuk J, Wrobel M, Kotwica J. (2011) The adverse effect of phytoestrogens on the secretory activity of bovine granulosa and luteal cells: involvement in oxytocin synthesis and secretion. Reprod. Dom. Anim. 46, 21-28.
  2. Wrobel MH, Mlynarczuk J, Kotwica J. (2010) Influence of polychlorinated biphenyls and their hydroxylated metabolites on prostaglandins secretion from epithelial cells of bovine oviduct, in vitro. Toxicology 270, 85-91.
  3. Mlynarczuk J, Wrobel MH, Kotwica J. (2010) Effect of environmental pollutants on oxytocin synthesis and secretion from corpus luteum and on contractions of uterus from pregnant cows. Toxicol Appl Pharmacol 247, 243-249.
  4. Rekawiecki R, Nowocin A, Kotwica J. (2010) Relationship between concentrations of progesterone, oxytocin, noradrenaline, gene expression and protein level for their receptors in corpus luteum during estrous cycle in the cow. Prostaglandins Other Lipid Mediat. 92, 13-18.
  5. Mlynarczuk J, Rekawiecki R (2010). The role of the orphan receptor SF-1 in the development and function of the ovary. Reprod. Biol. 10, 177-193.
  6. Wróbel M, Młynarczuk J, Kotwica J, (2009) The adverse effect of dihydrodiphenyltrichloroetane (DDT) and its metabolite (DDE) on the secrertion of prostaglandins and oxytocin in bovine cultured ovarian and endometrial cells. Reprod. Toxicol. 27, 72-78.
  7. Sirotkin AV, Rafay J, Kotwica J, Darlak K, Valenzuela F. (2009). Role of ghrelin in regulating rabbit ovarian function and the response to LH and IGF-I. Dom. Anim. Endocrinol. 36, 162-172.
  8. Benčo, A.V. Sirotkin,, D.Vašíček,, S. Pavlová,, J. Zemanová, J. Kotwica, K. Darlak, F. Valenzuela. (2009). Involvement of the hormone ghrelin and transcription factor STAT-1 in the regulation of porcine ovarian granulosa cell functions. Reproduction 138, 553–560.
  9. Kowalik M.K, Slonina D, Kotwica J. (2009) Genomic and non-genomic effect of progesterone (P4) and pregnenolone (P5) on the function of bovine endometrial cells. Vet. Med.-Czech, 54, 205–214
  10. Sirotkin, A.V. Rafay, J. Kotwica, J. (2009) Leptin controls rabbit ovarian function in vivo and in vitro: Possible interrelationships with ghrelin. Theriogenology, 72, 765–772.
  11. Wrobel HM, Rekawiecki R, Kotwica J. (2009). Involvement of prostaglandin F2α in the adverse effect of PCB 77 on the force of contractions of bovine myometrium. Toxicology,  262, 224-229.
  12. Mlynarczuk J, Wrobel M, Kotwica J. (2009). The influence of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite - dichlorodiphenyldichloroethylene (DDE) on mRNA expression for NP-I/OT and PGA, involved in oxytocin synthesis in bovine granulosa and luteal cells. Reprod. Toxicol. 28, 354-358.
  13. Slonina D, Kowalik MK, Subocz M, Kotwica J. (2009) Genomic and non-genomic effect of ovarian steroids on oxytocin-stimulated secretion and synthesis of prostaglandins in bovine myometrial cells. Prostaglandins Other Lipid Mediat. 90, 69-75.
  14. Franczak A., Kurowicka B., Kowalik M., Ciereszko R.E., Kotwica G. (2009) The effect of oxytocin on progesterone secretion, phosphoinositide hydrolysis and intracellular mobilisation of Ca2+ in porcine luteal cells Acta Vet Hung 57, 75-89.

Wykaz publikacji za lata 2000 - 2008

  1. Rekawiecki R, Kowalik MK, Słonina D, Kotwica J. (2008) Regulation of progesterone synthesis and action in bovine corpus luteum. J. Physiol. Pharmacol. 59, Suppl 9, 75-89.
  2. Kowalik MK, Kotwica J, (2008) Progesterone receptor membrane component 1 (PGRMC1) gene expression in corpus luteum during estrous cycle in cows.  Reprod. Biol. 8, 293-299.
  3. Młynarczuk J, Wróbel M, Kotwica J. (2008) Ekspresja genów dla NP-I/OT i PGA w komórkach lutealnych i warstwy ziarnistej pęcherzyka jajnikowego i czynnika LIF w komórkach endometrium krowy pod wpływem DDT i jego metabolitów. Med. Wet. 64, 579-582.
  4. Rękawiecki R, Kotwica J. (2008) Involvement of progesterone, oxytocin and noradrenaline in the molecular regulation of steroidogenesis in corpus lutem of the cow. Bull. Vet. Inst. Pulawy 52, 573-580.
  5. Sirotkin AV, Benčo A, Tandlmajerova A, Perkins N, Vašíček D,, Kotwica J, Darlak K, Valenzuela F. (2008).  Transcription factor p53 can regulate proliferation, apoptosis and secretory activity of luteinizing porcine ovarian granulosa cell cultured with and without ghrelin and FSH. Reproduction, 136, 611-618.
  6. Rękawiecki R, Kotwica J. (2007) Molecular regulation of progesterone synthesis in the bovine corpus luteum. Veterinarni Medicina, 52, (8), 405-412.
  7. Kowalik M, Kotwica J. (2007) Nongenomic effect of ovarian steroids on oxytocin-stimulated prostaglandin (PG) F2α and E2 secretion from bovine endometrial cells. Bull. Inst. Vet. Pulawy, 51, 37-42.
  8. Wrobel M. Kotwica J. (2007) Phytoestrogens reduce the effect of polychlorinated biphenyls on the contractility of bovine myometrium in vitro. Veterinarni Medicina.52, 55-62.
  9. Młynarczuk J, Kotwica J. (2006) Effect of polychlorinated biphenyls on the secretion of oxytocin from luteal and granulosa cells in cow: possible involvement of glucocorticoid receptors. Vet-Med Czech 51, 390-397.
  10. Kotwica J. Wrobel M, Młynarczuk J. (2006)The influence of polychlorinated biphenyls (PCBs) and phytoestrogens in vitro on functioning of reproductive tract in cow. Reprod. Biol. 6 (Suppl. 1) 189-194.
  11. Młynarczuk J, Kotwica J. (2006) Influence of polychlorinated biphenyls (PCBs) on LH-stimulated secretion of progestereone and oxytocin from bovine luteal cells obtained on different days of estrous cycle. Pol. J. Vet. Sci. 9, 101-108.
  12. Wrobel M, Kotwica J. (2005) Influence of polychlorinated biphenyls (PCBs) and phytoestrogens on prostaglandins F2α and E2 secretion from bovine endometrial cells at postovulatory stage of the estrous cycle Vet-Med Czech 50, 487-495.
  13. Młynarczuk JJ, Niewiadowska A, Kotwica J. (2005) Polychlorinated biphenyls impair FSH - stimulated effect on the secretion of steroids and oxytocin from cultured bovine granulosa cells. Bull. Inst Vet. Pulawy 49, 411-417.
  14. Młynarczuk J, Kotwica J. (2005) Influence of polichlorinated biphenyles on the secretion of oxytocin from bovine luteal cells and from granulosa cells obtained from the follicles of different size. Pol. J. Vet. Sci. 8, 261-267.
  15. Wróbel M, Kotwica J (2005)  Effect of polychlorinated biphenyls on basal and OT-stimulated calcium concentrations in myometrial cells in cow. Reprod. Biol. 5, 321-330.
  16. Wróbel M, Kamiński K, Kotwica J (2005) In vitro effect of polychlorinated biphenyls (PCBs) on contractility of bovine myometrium from periovulatory stage of the estrous cycle. Reprod. Biol. 5,. 303-319.
  17. Rekawiecki R, Nowik M, Kotwica J. (2005) Stimulatory effect of LH, PGE2 and noradrenaline on StAR protein, cytochrome P450 cholesterol side chain cleavage and 3b-hydroxysteroid dehydrogenase gene expression in bovine luteal cells: Possible mediation through progesterone. Prostaglandins Other Lipid Mediat. 78, 169-184
  18. Liszewska E, Rekawiecki R, Kotwica J. (2005) Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells. Prostaglandins Other Lipid Mediat. 78,67-81.
  19. Sirotkin AV, Mlyncek M, Kotwica J, Makarevich AV, Florkovicova I, Hetenyi L. (2005) Leptin directly controls secretory activity of human ovarian granulose cells: possible inter-relationship with the IGF/IGFBP system. Hormone Research 64, 198-202.
  20. Duras M, Brzósko E, Kotwica J. (2005) Influence of progesterone, pregnenolone and 17β-hydroxy-progesterone on the function of bovine luteal cells treated with luteinizing hormone, noradrenaline and prostaglandin E2. Pol. J. Vet. Sci. 8, 113-119.
  21. Młynarczuk J, Sąsiadek J, Kotwica J. (2005) Non genomic action of progesterone in luteal and endometrial epithelial cells in cattle. Bull. Inst. Vet. Pulawy. 49, 193-198.
  22. Duras M, Mlynarczuk J, Kotwica J. (2005) Non-genomic effect of steroids on oxytocin-stimulated intracellular mobilization of calcium and on prostaglandin F2α and E2 secretion from bovine endometrial cells. Prostaglandins Other Lipid Mediat. 76, 105-116.
  23. Kotwica J (2004) Involvement of arachidonic acid and its products in the mechanism of progesterone influence on its own production in the corpus luteum of cow in vitro. Bull. Inst. Vet. Pulawy  48, 259-264.
  24. Sirotkin AV, Stanislo P, Schaeffer H-J, Florcikova I, Kotwica J, Bulla J, Hetenyi L. (2004) Thrombopoietin regulates proliferation, apoptosis, secretory activity and intracellular messengers in porcine ovarian follicular cells: involvement of protein kinase A. J. Endocrinol. 183, 595-604.
  25. Kotwica J, Rekawiecki R, Duras M. (2004) Stimulatory influence of progesterone on its own synthesis in bovine corpus luteum. Bull. Inst. Vet. Pulawy 48, 139-145.
  26. Kotwica J, Młynarczuk J, Duras M, Amarowicz R. (2003) Relationship between progesterone and ovarian oxytocin within corpus luteum in cow. Bull. Inst. Vet. Pulawy 47, 449-457.
  27. Mlynarczuk J, Amarowicz R, Kotwica J. (2003) Effect of polichlorined biphenyls (Aroclor-1248) on secretory function of bovine luteal cells modified by LH noradrenaline and high density lipoproteins. Vet-Med Czech 48, 267-274.
  28. Sirotkin AV, Makarevich AV, Kwon HB, Kotwica J, (2003) Involvement of MAP kinase in the mediation of GH action on ovarian granulosa cells. Mol. Cell Endocrinol. 205, 193-199.
  29. Kotwica G, Kurowicka B, Franczak A, Grzegorzewski W, Wrobel M, Mlynarczuk J, Kotwica J. (2003) The concentrations of catecholamines and oxytocin receptors in the oviduct and its contractile activity in cows during the estrous cycle. Theriogenology, 60, 953-964.
  30. Sirotkin AV, Florkovicova I., Makarevich AV, Schaeffer H-J., Kotwica J, Marnet P-G, Sanislo P. (2003) Oxytocin mediates some effects of insulin-like growth factor-I on porcine ovarian follicles. J. Reprod. Develop. 49, 141-149.
  31. Skarzynski D., Młynarczuk J., Kotwica J. (2003) Involvement of high-density lipoprotein in stimulatory effect of hormones supporting function of bovine corpus luteum. Acta Vet. Hung. 51, 111-120.
  32. Kotwica J, Skarzynski D, Mlynarczuk J, Rekawiecki R. (2003) Role of prostaglandin E2 in basal and noradrenaline-induced progesterone secretion from corpus luteum in cow. Prostaglandins and Other Lipid Mediat. 70, 351-359.
  33. Bogacki M., Silvia WJ, Rękawiecki R. Kotwica J. (2002) Direct inhibitory effect of progesterone on oxytocin-induced secretion of prostaglandin F2a from bovine endometrial tissue. Biol. Reprod. 67, 184-188.
  34. Kotwica J., Bogacki M., Rekawiecki R. (2002) Neural regulation of corpus luteum in cow. Dom. Anim. Endocrinol. 23, 299-308.
  35. Sirotkin AV, Makarevich AV, Corkins MR, Kotwica J, Kwon HB, Bulla J, Hetenyi L (2001) Secretory activity of bovine ovarian granulosa cells transfected with sense and antisense insulin-like growth factor (IGF) binding protein-3 and the response to IGF-I, GH, LH, oxytocin and oestradiol. J. Mol. Endocrinol. 27, 329-338.
  36. Sirotkin AV, Makarevich AV, Kwon HB, Kotwica J, Bulla J, Hetenyi L. (2001) Do GH, IGF-I and oxytocin interact by regulating the secretory activity of porcine ovarian cells? J. Endocrinol. 171, 475-480.
  37. Sirotkin AV, Makarevich AV, Corkins MR, Kotwica J. Bulla J. (2001) The transfection-induced overexpression of IGF-binding protein-4 affects the secretory activity of porcine ovarian granulosa cells and their response to hormones and IGF-I. J. Mol. Endocrinol. 26, 241-248.
  38. Miszkiel G., Kotwica J. (2001) Mechanism of action of noradrenaline on secretion of progesterone and oxytocin by the bovine corpus luteum in vitro. Acta vet. Hung. 49, 39-51.
  39. Sirotkin A., Makarevich A., Pivko, J., Kotwica J., Geniesser H.G., Bulla J. (2000) Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro. J.Steroid Biochem. Mol. Biol. 74, 1-9.
  40. Kotwica J, Jaroszewski J, Bogacki M. (2000) Lack of ovarian response in ageing cows to noradrenaline infused into the abdominal aorta. Pol. J. Vet. Sci. 4, 239-241.
  41. Sienkiewicz W, Kaleczyc J, Wąsowicz K, Czaja K, Pidsudko Z, Kotwica J, Łakomy M. (2000) The influence of active immunisation against GnRH on adrenergic innervation of the porcine testis, epididymis and vas diferens. A quantitative and morphological study. Pol. J. Vet. Sci. 3, 131-140.
  42. Sirotkin AV, Makarevich AV, Genieser HG, Kotwica J, Hetenyi L (2000) Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro.  Exp. Clin. Endocrinol. Diabet. 108, 214-219.
 

Oddział BIologii Rozrodu

ul. Bydgoska 7, 10-243 Olsztyn

tel. +48 89 535 74 22

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zakład fizjologii
i toksykologii rozrodu


Pracownicy

Kierownik

prof. dr hab. Jan Kotwica


Adiunkci

dr Magdalena Kowalik

dr Robert Rękawiecki

dr. n. wet. Jarosław Młynarczuk

dr Michał Wróbel

 

Pracownicy techniczni

mgr Beata Czarkowska

mgr Beata Ustjanowska

Beata Jarmicka

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